Intravenous Thrombolysis Use before Inter‐Facility Transfer for Thrombectomy: Association with Efficacy and Safety Outcomes

IVT before transfer was associated with improved recanalization and functional outcomes without increasing safety risks but is used in only 50% of patients. Expanding IVT criteria, including treatment beyond 4.5 hours and in anticoagulated patients, should be explored. ANN NEUROL 2025;98:871-880.

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Publication Details

Journal
Annals of Neurology
Published
2025-06-19
DOI
https://doi.org/10.1002/ana.27303
Citations
3
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
4.06

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article

Intravenous Thrombolysis Use before Inter‐Facility Transfer for Thrombectomy: Association with Efficacy and Safety Outcomes

Maarten G. Lansberg, Jeremy Josef Heit, Pierre Seners, Michael Mlynash et al.
3 citations
Annals of Neurology
Acute Ischemic Stroke Management
4.06
article

Intravenous Thrombolysis Use before Inter‐Facility Transfer for Thrombectomy: Association with Efficacy and Safety Outcomes

Maarten G. Lansberg, Jeremy Josef Heit, Pierre Seners, Michael Mlynash, Thibault Lalu, Gregory W. Albers, Vincent Costalat, Anke Wouters, Denis Sablot, Anne Wacongne, Adrien ter Schiphorst, Nicole Yuen, Caroline Arquizan
article en
3 citations

Abstract

IVT before transfer was associated with improved recanalization and functional outcomes without increasing safety risks but is used in only 50% of patients. Expanding IVT criteria, including treatment beyond 4.5 hours and in anticoagulated patients, should be explored. ANN NEUROL 2025;98:871-880.

Annals of NeurologyVol. 98(4)
Inserm (FR), Université Paris Cité (FR), Centre Hospitalier de Perpignan (FR), Centre Hospitalier de Béziers (FR), Centre Hospitalier Universitaire de Nîmes (FR), Hôpital Gui de Chauliac (FR), Fondation de Rothschild (FR), Institut de Psychiatrie et Neurosciences de Paris (FR), Stanford Medicine (US), Stanford University (US), KU Leuven (BE)
Philippe Foundation, Fonds Wetenschappelijk Onderzoek, Fondation Bettencourt Schueller, Servier, Vlaamse regering, Edmond de Rothschild Foundation, Institut Servier, National Institutes of Health
Good health and well-being
Openalex Percentile: Top 6%
Acute Ischemic Stroke Management
4.06
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