External beam radiation therapy for cell carcinoma of the anal canal: preparation, planning, details of treatment

In the absence of a unified approach in numerous recommendations and consensuses for chemoradiotherapy of patients with squamous cell non-metastatic anal canal cancer, medical practitioners need a practical consolidating “tool” combining all information sources, which is the purpose of this article.Based on international recommendations and consensuses on radiation therapy, the expert group analyzed the data and compiled the most optimal approaches to target volume delineation. This was done based on a balanced analysis of the advantages and disadvantages of the fractionation modes used and the criteria for dose distribution in irradiated apparatus proposed by both other authors and the team of the radiotherapy department of the N. N. Blokhin National Medical Research Center of Oncology. Examples of delineating anatomical structures and target volumes are provided.