Tear Cytokine Changes up to One Year After Allogeneic Hematopoietic Stem Cell Transplant: Effect of Daily Topical Cyclosporine-A 0.1% Emulsion
HSCT induces significant elevation of 38 tear cytokines/chemokines even without the occurrence of ocular graft-versus-host disease when systemic immunosuppression is reduced within the first year. Topical daily cyclosporine eyedrops can reduce some pro-inflammatory tear cytokines.
Authors
- Francesca Lim (ORCID: https://orcid.org/0000-0001-7194-2845)
- William Ying Khee Hwang (ORCID: https://orcid.org/0000-0003-0143-6263)
- Li Lim (ORCID: https://orcid.org/0000-0003-1144-5737)
- Jeffrey Kim Siang Quek
- Hein Than (ORCID: https://orcid.org/0000-0003-1056-083X)
- Isabelle Xin Yu Lee
- Sharon Yeo (ORCID: https://orcid.org/0000-0002-4168-6710)
- Aloysius Yew Leng Ho (ORCID: https://orcid.org/0000-0003-1299-8560)
- Yeh Ching Linn (ORCID: https://orcid.org/0000-0001-8098-2590)
- Chang Liu (ORCID: https://orcid.org/0000-0003-4641-5108)
- Yu‐Chi Liu (ORCID: https://orcid.org/0000-0001-5408-0382)
- Louis Tong (ORCID: https://orcid.org/0000-0002-3986-6552)
Institutions
- National University of Singapore (SG)
- Singapore General Hospital (SG)
- Singapore National Eye Center (SG)
- Singapore Eye Research Institute (SG)
Publication Details
- Journal
- International Journal of Molecular Sciences
- Published
- 2025-06-19
- DOI
- https://doi.org/10.3390/ijms26125915
- Citations
- 2
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 3.76
Funders
- Santen
- National Medical Research Council