The Use of Probiotics in Mental Health

This review focuses on the potential health benefits of probiotics and live microorganisms as therapeutic agents for mental and emotional disorders. Through mechanisms, including modulation of immune responses, control of the hypothalamic-pituitary-adrenal (HPA) axis, maintenance of the gut barrier, and synthesis of important neurotransmitters, we examined their effects on anxiety, depression, stress-related disorders, cognitive function, and emotional well-being. Some clinical trials have shown positive results, and the generalizability of these findings is limited due to inconsistencies in probiotic strains, dosages, and research methods, although several studies have reported beneficial results. Ultimately, this study highlights the potential of tailored probiotics to fill these gaps in our understanding of the relationship between humans and probiotics.

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Publication Details

Journal
Journal of Biomedical Science and Engineering
Published
2025-01-01
DOI
https://doi.org/10.4236/jbise.2025.186015
Primary Topic
Health, psychology, and well-being
Type
article
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article

The Use of Probiotics in Mental Health

Noorah Saleh Al-Sowayan, Shahad AL-Farhood
Journal of Biomedical Science and Engineering
Health, psychology, and well-being
article

The Use of Probiotics in Mental Health

Noorah Saleh Al-Sowayan, Shahad AL-Farhood
article en

Abstract

This review focuses on the potential health benefits of probiotics and live microorganisms as therapeutic agents for mental and emotional disorders. Through mechanisms, including modulation of immune responses, control of the hypothalamic-pituitary-adrenal (HPA) axis, maintenance of the gut barrier, and synthesis of important neurotransmitters, we examined their effects on anxiety, depression, stress-related disorders, cognitive function, and emotional well-being. Some clinical trials have shown positive results, and the generalizability of these findings is limited due to inconsistencies in probiotic strains, dosages, and research methods, although several studies have reported beneficial results. Ultimately, this study highlights the potential of tailored probiotics to fill these gaps in our understanding of the relationship between humans and probiotics.

Journal of Biomedical Science and EngineeringVol. 18(06)
Qassim University (SA), Buraydah Colleges (SA)
Zero hunger
Openalex Percentile: Top 76%
Health, psychology, and well-being
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The Use of Probiotics in Mental Health — Noorah Saleh Al-Sowayan, Shahad AL-Farhood · Journal of Biomedical Science and Engineering (2025) | TGRS Research Map | TGRS