PET/CT acquisition and processing protocols in the Netherlands
The main objective of this survey was to determine the current state of practice in the Netherlands for three common PET/CT examinations. We observed variations in the injected activity for all PET/CT exam types, even within the same scanner model, that cannot be explained by taking into account differences in scanning times or uptake times. The direct implication of the observed variation in injected activity is a similar variation in radiation dose to the patient. We observed differences in dose to the patient of up to a factor 4 for FDG-WB, more than a factor of 5for [<sup>18</sup>F]F-PSMA, a factor of 4 for [<sup>68</sup> Ga]Ga-PSMA, and up to a factor of 5 for FDG-brain scans. Variations in count statistics, reconstruction, and processing settings for similar-weight patients on comparable PET/CT systems should be further investigated for their impact on lesion detectability.
Authors
- Koen van Gils (ORCID: https://orcid.org/0000-0001-8391-0349)
- A. J. van Lange (ORCID: https://orcid.org/0000-0003-0395-7476)
- Niels C. Veltman
- Oleksandra Ivashchenko (ORCID: https://orcid.org/0000-0001-8675-8987)
- Pepijn van Horssen
- Adriaan A. Lammertsma (ORCID: https://orcid.org/0000-0003-1237-2891)
- Dennis Dieckens (ORCID: https://orcid.org/0000-0001-5651-5116)
- Wouter J. H. Veldkamp (ORCID: https://orcid.org/0000-0002-6293-8956)
Institutions
- University Medical Center Groningen (NL)
- Leiden University Medical Center (NL)
- Hotel Dieu Hospital (CA)
- Albert Schweitzer Ziekenhuis (NL)
- Meander Medisch Centrum (NL)
- Jeroen Bosch Ziekenhuis (NL)
Publication Details
- Journal
- EJNMMI Physics
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1186/s40658-025-00770-3
- Citations
- 2
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.72