Single-cell atlas of human skin implicates APOE pro-inflammatory signaling in diabetic foot ulcers
This study provides critical insights into the differences between healthy and DFU fibroblasts, identifying specific cell populations that may influence DFU healing. These findings may contribute to future therapeutic development for DFU.
Authors
- Mingen Liu (ORCID: https://orcid.org/0009-0000-0790-0456)
- Yating Yin
- Li Li (ORCID: https://orcid.org/0000-0002-4904-7075)
- Bin Wang (ORCID: https://orcid.org/0000-0003-3392-7745)
Institutions
- Shanghai Ninth People's Hospital (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Seventh People's Hospital of Shanghai (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-19
- DOI
- https://doi.org/10.3389/fimmu.2025.1591944
- Citations
- 1
- Primary Topic
- Diabetic Foot Ulcer Assessment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- National Natural Science Foundation of China