Integrated multi-omics analysis reveals the immunotherapeutic significance of tumor cells with high FN1 expression in ovarian cancer
A prognostic model created based on FN1 tumor cells provided a new idea for clinical staging of ovarian cancer patients. Meanwhile, this study provided new insights into the heterogeneity of tumor cells and suggested a potential therapeutic target, FN1, which could be helpful for precise immunotherapy of ovarian cancer.
Authors
- Qing Wu
- Zhikai Xiahou
- Wei Nie
- Shouyan Wang (ORCID: https://orcid.org/0000-0002-9776-8539)
- Fu Zhao (ORCID: https://orcid.org/0000-0002-5286-5650)
- Xinyi Zhang (ORCID: https://orcid.org/0000-0002-0581-9707)
Institutions
- Jinan University (CN)
- Southwest Medical University (CN)
- Shandong Provincial Hospital (CN)
- Beijing Sport University (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-06-19
- DOI
- https://doi.org/10.3389/fmolb.2025.1611964
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.87