Comparative cardiomyocyte differentiation potential of rat adipose-derived mesenchymal stem cells from two anatomical sites: metabolomic profiling and pathway analysis
The anatomical origin of AD-MSCs influences their metabolic landscape during cardiomyocyte differentiation. Peri-ovarian AD-MSCs demonstrated greater metabolic adaptability, potentially favoring their differentiation capacity, making them a promising candidate for cardiac regenerative applications.
Authors
- Haney Samir (ORCID: https://orcid.org/0000-0002-0594-3986)
- Masahiro Kaneda (ORCID: https://orcid.org/0000-0003-0660-7156)
- Ken Takahashi (ORCID: https://orcid.org/0000-0002-7580-8691)
- Sai Koung Ngeun (ORCID: https://orcid.org/0009-0003-2732-0717)
- Ryou Tanaka (ORCID: https://orcid.org/0000-0001-9948-6490)
- Hanan A. Hendawy (ORCID: https://orcid.org/0000-0003-4576-7646)
- Ahmed Farag (ORCID: https://orcid.org/0000-0002-1953-4294)
Institutions
- Suez Canal University (EG)
- Cairo University (EG)
- Zagazig University (EG)
- National Center of Neurology and Psychiatry (JP)
- Juntendo University Urayasu Hospital (JP)
- Tokyo University of Agriculture and Technology (JP)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-06-19
- DOI
- https://doi.org/10.3389/fcell.2025.1604605
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00