Analysis of gut and circulating microbiota characteristics in patients with liver cirrhosis and portal vein thrombosis
Intestinal dysbiosis and translocation in cirrhotic patients with PVT lead to differential changes in the portal and peripheral circulatory microbiomes. This may contribute to the formation of PVT by inducing endotoxemia and systemic inflammation, providing a new microbiological perspective on the pathogenesis of cirrhosis-related PVT through the gut-liver axis.
Authors
- Xinxin Yang (ORCID: https://orcid.org/0000-0002-2024-4307)
- Wei Sang (ORCID: https://orcid.org/0000-0002-1170-7074)
- Yun Bai (ORCID: https://orcid.org/0000-0001-9472-0196)
- Chong Wang (ORCID: https://orcid.org/0000-0001-7278-6119)
- Wei Zhang (ORCID: https://orcid.org/0000-0002-2322-642X)
- Ping Qi
Institutions
- Hebei North University (CN)
- Hebei General Hospital (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-06-19
- DOI
- https://doi.org/10.3389/fmicb.2025.1597145
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71