Metabolic acidosis as a risk factor for bronchopulmonary dysplasia in preterm infants born between 23 + 0 and 31 + 6 weeks of gestation: a retrospective case-control study

Metabolic acidosis on DOL 6 was associated with an increased risk of moderate/severe BPD or mortality, suggesting its potential role as a modifiable risk factor. While excessive fluid intake has been linked to BPD, our findings highlight the complexity of fluid management in preterm infants. Further research is needed to determine whether correcting metabolic acidosis could improve respiratory outcomes.