Oxytropis falcata bunge extract combined with black soybean oil ameliorates DNCB-induced atopic dermatitis-like skin inflammation
The combination of OFE and BSO can effectively reduce DNCB-induced atopic dermatitis in mice. Its action does not rely on broad immunosuppression or induce skin toxicity and may involve inhibition of proinflammatory cytokine release and downregulation of the HDAC3/NF-κB signaling pathway.
Authors
- Rupei Chen (ORCID: https://orcid.org/0009-0005-9945-097X)
- Jinjin Kai
- Yan Chen (ORCID: https://orcid.org/0000-0002-2166-3132)
- Yan Wu (ORCID: https://orcid.org/0000-0002-9552-3677)
- Meng Liu (ORCID: https://orcid.org/0000-0002-6960-3163)
- Jihua Tian (ORCID: https://orcid.org/0000-0003-1508-4262)
- Xianwei Wu (ORCID: https://orcid.org/0009-0007-4366-4586)
- Qianya Zhao (ORCID: https://orcid.org/0009-0000-8677-5576)
- Jiachen Bu
Institutions
- Gansu University of Traditional Chinese Medicine (CN)
- Gansu Provincial Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-06-19
- DOI
- https://doi.org/10.3389/fphar.2025.1549492
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Gansu Province