SNRPB2 facilitates esophageal squamous cell carcinoma oncogenesis and progression via E2F4 stabilization
SNRPB2 promotes ESCC progression by stabilizing E2F4 and regulating cell cycle genes. It is also associated with immune infiltration and gene expression in ESCA. SNRPB2 may serve as a prognostic biomarker and potential therapeutic target in esophageal cancer.
Authors
- Feng Xu (ORCID: https://orcid.org/0000-0001-6888-8753)
- Guangyao Ning
- Ren-Quan Zhang
- Lu Chen (ORCID: https://orcid.org/0009-0009-4731-1264)
- Chan Zhu (ORCID: https://orcid.org/0000-0003-4131-3495)
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-19
- DOI
- https://doi.org/10.3389/fimmu.2025.1610721
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00