[18F]-fluorocholine long-axial-field of view PET-CT accurately localises intrathyroid parathyroid adenoma in 5-month pregnant patient
The patient needed multiple hospitalisations and was at risk of foetal and maternal complications.Exploratory neck surgery was unsuccessful.We performed a low-dose PET-CT to minimise radiation exposure to the foetus [2].The patient was injected with 17 MBq (0.2 MBq/kg) and scanned for 30 min from vertex to diaphragm, 62 min post-injection using a Biograph Vision Quadra PET-CT (Siemens Healthineers, Erlangen, Germany).CT was performed with CAREDose on (reference mAs = 65), CAREkV reference 120 kV.[ 18 F]-fluorocholine LAFOV PET-CT demonstrated focal intense choline uptake in a low density intrathyroid left lower pole nodule, consistent with a parathyroid adenoma (A: MIP, B: axial CT and C: fused axial images).An uncorrected PET-only acquisition was performed to calculate the foetal dose, which was estimated at 0.5 mSv from PET and 0.1 mGy from CT.
Authors
- Bruno Roberto da Silva Ferreira (ORCID: https://orcid.org/0000-0002-5167-4684)
- Piyumi Wijewickrama (ORCID: https://orcid.org/0000-0001-7260-1727)
- Tamar Willson
- Thomas Wagner (ORCID: https://orcid.org/0000-0002-3867-6829)
- Beverley F. Holman
- J M Edwards
Institutions
- Royal Free London NHS Foundation Trust (GB)
- Royal Sussex County Hospital (GB)
- Thomas Young Centre (GB)
- University College London (GB)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1007/s00259-025-07417-6
- Citations
- 2
- Primary Topic
- Parathyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.86