Systemic Review of Clinical Presentation of Duchenne Muscular Dystrophy Patients: A Focused Case Series from King Saud Medical City, Saudi Arabia

Duchenne Muscular Dystrophy (DMD) is one of the most common and devastating genetic disorders affecting children, predominantly boys. [1] is an X-linked recessive condition caused by mutations in the dystrophin gene, leading to the absence or significant reduction of dystrophin, a protein essential for maintaining muscle cell integrity. [2]This deficiency results in progressive muscle degeneration, loss of motor function, and eventual multisystem involvement. [3]Globally, the incidence of DMD is estimated at approximately 1 in 3,500 male live births. [4]Despite advances in genetic and molecular biology, the disease remains incurable, with most patients relying on