Evaluating the introduction of COVID-19 oral antivirals through a test and treat program: outcomes from a cohort study in four African countries

These data are the first to suggest COVID-19 oral antiviral treatment can be quickly, efficiently and safely deployed in lower- and middle-income countries, in parallel with implementation research. Programs rapidly integrated their COVID-19 response into existing health service infrastructure, allowing for decentralization and demonstrating that introducing newly developed diagnostics and treatment in government health systems is feasible in lower-resourced settings during health emergencies. Equitable and timely access to diagnostics and treatments is crucial to combat emerging global disease threats and achieve global health equity.

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Publication Details

Journal
International Journal of Infectious Diseases
Published
2025-06-19
DOI
https://doi.org/10.1016/j.ijid.2025.107956
Citations
1
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
1.40

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article

Evaluating the introduction of COVID-19 oral antivirals through a test and treat program: outcomes from a cohort study in four African countries

Nyuma Mbewe, Jessica Joseph, Christian B. Ramers, Sabine Umuraza et al.
1 citations
International Journal of Infectious Diseases
SARS-CoV-2 and COVID-19 Research
1.40
article

Evaluating the introduction of COVID-19 oral antivirals through a test and treat program: outcomes from a cohort study in four African countries

Nyuma Mbewe, Jessica Joseph, Christian B. Ramers, Sabine Umuraza, Edson Rwagasore, Lawrence Ofori-Boadu, Caroline E. Boeke, Maria V. Grau‐Sepulveda, Mwaba Mulenga, Alexander Martin-Odoom, Bridget C. Griffith, Cameron R. Wolfe, Dyson Telela, Shanti Narayansamy, Norman Lufes
article en
1 citations

Abstract

These data are the first to suggest COVID-19 oral antiviral treatment can be quickly, efficiently and safely deployed in lower- and middle-income countries, in parallel with implementation research. Programs rapidly integrated their COVID-19 response into existing health service infrastructure, allowing for decentralization and demonstrating that introducing newly developed diagnostics and treatment in government health systems is feasible in lower-resourced settings during health emergencies. Equitable and timely access to diagnostics and treatments is crucial to combat emerging global disease threats and achieve global health equity.

International Journal of Infectious DiseasesVol. 158
Ministry of Health (GH), Duke University (US), Clinical Research Institute (US), Public Health Institute of Malawi (MW), Clinton Health Access Initiative (US), Duke Institute for Health Innovation (US), Ministry of Health (MW), Zambia National Public Health Institute (ZM), Rwanda Biomedical Center (RW), National Institute of Public Administration (ZM), Ministry of Health (RW)
Conrad N. Hilton Foundation, Open Society Foundations, Pfizer, Rwanda Biomedical Centre, Duke Global Health Institute, Duke University, School of Medicine, Duke University, Duke Clinical Research Institute
Openalex Percentile: Top 19%
SARS-CoV-2 and COVID-19 Research
1.40
DOIOpen Access PDFOpenAlex
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