Clinicopathological and molecular characterization of contagious caprine pleuropneumoniae (CCPP) in goats

The present study was carried out to clinicopathological changes in goats affected with contagious caprine pleuropneumoniae. A Total of 751 goats from six districts (Chittoor, Nellore, Tirupati, Annamayya, Kadapa and N.T.R district) of Andhra Pradesh were examined. The main clinical signs observed in affected flocks were fever, anorexia, nasal discharge, coughing, polypnoea, and dyspnoea. In the post mortem examination gross appearance of infected lung tissues shows hepatization, various level of marbling and adhesion of lung to pleura. On histopathological examination revealed that thickening of pleura and interlobular septa with fibrous tissue separating lung into lobules. Molecular confirmation was also carried by using PCR yielding 316bp product targeting arcD gene.