Effective treatment of refractory aplastic anemia with romiplostim after failure of multiple thrombopoietin receptor agonists: a single-center retrospective study
High-dose ROM with an initial dosage of 20 μg/kg per week is effective and safe for patients with refractory AA who experienced treatment failure with IST and multiple oral TPO-RAs, exerting a rapid response.
Authors
- Bing Han (ORCID: https://orcid.org/0000-0002-9717-217X)
- Xijuan Lin (ORCID: https://orcid.org/0009-0005-8754-0388)
- Chen Yang (ORCID: https://orcid.org/0000-0002-1415-8752)
- Junling Zhuang (ORCID: https://orcid.org/0000-0002-1228-0551)
- Miao Chen (ORCID: https://orcid.org/0000-0002-8002-6651)
- Ziwei Liu (ORCID: https://orcid.org/0009-0005-4275-4710)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1080/07853890.2025.2514791
- Citations
- 1
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- National Natural Science Foundation of China