Pilot determination of reference intervals for sorbitol in cattle

A pilot study was conducted to determine reference intervals for sorbitol in cattle. The study determined the level of sorbitol in the urine of cattle. It was found that the endogenous concentration of sorbitol in animals to which it was not administered was below the sensitivity threshold of the spectrophotometer. Extremely close values of sorbitol concentration in males and females were explained. A description of the pharmacokinetics of sorbitol in the body of males and females of cattle is presented. It was found that sex hormones and sex differences in organisms do not have a significant effect on the pharmacokinetics of sorbitol. Further paths for scientific research on the clearance of sorbitol and its use in veterinary medicine are proposed.

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Publication Details

Journal
BIO Web of Conferences
Published
2025-01-01
DOI
https://doi.org/10.1051/bioconf/202518101021
Primary Topic
Veterinary medicine and infectious diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Pilot determination of reference intervals for sorbitol in cattle

Vladimir Sergeevich Ponamarev
BIO Web of Conferences
Veterinary medicine and infectious diseases
article

Pilot determination of reference intervals for sorbitol in cattle

Vladimir Sergeevich Ponamarev
article en

Abstract

A pilot study was conducted to determine reference intervals for sorbitol in cattle. The study determined the level of sorbitol in the urine of cattle. It was found that the endogenous concentration of sorbitol in animals to which it was not administered was below the sensitivity threshold of the spectrophotometer. Extremely close values of sorbitol concentration in males and females were explained. A description of the pharmacokinetics of sorbitol in the body of males and females of cattle is presented. It was found that sex hormones and sex differences in organisms do not have a significant effect on the pharmacokinetics of sorbitol. Further paths for scientific research on the clearance of sorbitol and its use in veterinary medicine are proposed.

BIO Web of ConferencesVol. 181
St Petersburg University (RU), Saint Petersburg State University of Veterinary Medicine (RU)
Russian Science Foundation
Good health and well-being
Openalex Percentile: Top 84%
Veterinary medicine and infectious diseases
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