Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling
GXN may alleviate DMIRI by targeting <i>F. nucleatum</i> and PTEN related pathways, offering new insights into microbiota-based cardio protection.
Authors
- Longkun Liu
- Hongjun Yang (ORCID: https://orcid.org/0000-0001-5501-3288)
- Jing Cui (ORCID: https://orcid.org/0000-0001-8657-1741)
- Yue Liu (ORCID: https://orcid.org/0000-0002-0084-863X)
- Wenting Wang (ORCID: https://orcid.org/0000-0002-8344-0102)
- Yiwen Helen Li (ORCID: https://orcid.org/0000-0002-6874-0350)
- Yanfei Liu (ORCID: https://orcid.org/0000-0001-7706-6495)
- Mengmeng Zhu
- Qian Xu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Xiyuan Hospital (CN)
- China Academy of Chinese Medical Sciences (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-06-19
- DOI
- https://doi.org/10.3389/fphar.2025.1581413
- Primary Topic
- Medicinal Plants and Bioactive Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China