A Case of Accidental <i>Veratrum californicum</i> (California False Hellebore) Toxicity

The <i>Veratrum</i> genus of plants contains multiple toxic alkaloid compounds, and ingestion of <i>Veratrum</i> species may result in clinically significant human illness. Although many cases of <i>Veratrum</i> ingestion have been reported in the Eastern United States and Europe, no case report of human toxicity from the most common California species, <i>Veratrum californicum,</i> exists in the literature. We report on the clinical course and treatment of a patient with a known <i>Veratrum californicum</i> ingestion. We discuss the identification of the <i>Veratrum</i> species and compare our case to other cases of <i>Veratrum</i> ingestions reported in the literature. We find that similar to ingestions of other <i>Veratrum</i> species, our patient became hypotensive and bradycardic, requiring fluid resuscitation. Similar to other reports, our patient responded to treatment with atropine and was able to safely discharge after a short hospital stay. Our case adds the first reported ingestion of <i>Veratrum californicum</i> to the literature of other <i>Veratrum</i> ingestions and suggests that this toxicity similarly responds to atropine and hemodynamic support.

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Publication Details

Journal
Wilderness and Environmental Medicine
Published
2025-06-19
DOI
https://doi.org/10.1177/10806032251348162
Primary Topic
Hedgehog Signaling Pathway Studies
Type
article
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article

A Case of Accidental Veratrum californicum (California False Hellebore) Toxicity

Patil Armenian, Charizza Grace Besmanos, Caitlin Roake
Wilderness and Environmental Medicine
Hedgehog Signaling Pathway Studies
article

A Case of Accidental Veratrum californicum (California False Hellebore) Toxicity

Patil Armenian, Charizza Grace Besmanos, Caitlin Roake
article en

Abstract

The <i>Veratrum</i> genus of plants contains multiple toxic alkaloid compounds, and ingestion of <i>Veratrum</i> species may result in clinically significant human illness. Although many cases of <i>Veratrum</i> ingestion have been reported in the Eastern United States and Europe, no case report of human toxicity from the most common California species, <i>Veratrum californicum,</i> exists in the literature. We report on the clinical course and treatment of a patient with a known <i>Veratrum californicum</i> ingestion. We discuss the identification of the <i>Veratrum</i> species and compare our case to other cases of <i>Veratrum</i> ingestions reported in the literature. We find that similar to ingestions of other <i>Veratrum</i> species, our patient became hypotensive and bradycardic, requiring fluid resuscitation. Similar to other reports, our patient responded to treatment with atropine and was able to safely discharge after a short hospital stay. Our case adds the first reported ingestion of <i>Veratrum californicum</i> to the literature of other <i>Veratrum</i> ingestions and suggests that this toxicity similarly responds to atropine and hemodynamic support.

Wilderness and Environmental MedicineVol. 37(1)
University of California, San Francisco (US), California State University, Fresno (US)
Life in Land
Openalex Percentile: Top 87%
Hedgehog Signaling Pathway Studies
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