“A Comprehensive Review on Pilot Plant Scale up And Platform Technology”

The pharmaceutical business uses pilot plant scaleup strategies to create reliable manufacturing procedures and turn lab-scale formulas into commercial products. The place called Pilot is where the five elements Material, Man, Method, and Machine are combined to manufacture things. A tiny, basic lab scale formula will be tested on a replica of the intended plant in the pilot plant before spending a significant amount of money on a production unit. Scaling up a pilot plant provides information on formula examination, reviewing the range of pertinent processing equipment, understanding raw material specifications, production rate, and physical space requirements. It can hold accurate documentation and reports for analysis in support of the GMP procedure. This review research discusses the parameters such as granulation feed rate,compression parameters, temperature and rate of drying will have acritical role in development of any solid dosage form. The primary goal of a pilot plant is to identify errors on a small scale and generate revenue on a large scale.

Authors

Publication Details

Journal
International Journal of Pharmaceutical Research and Applications
Published
2025-03-01
DOI
https://doi.org/10.35629/4494-100312041221
Citations
1
Primary Topic
Drug Solubulity and Delivery Systems
Type
article
Field-Weighted Citation Impact
0.79
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article

“A Comprehensive Review on Pilot Plant Scale up And Platform Technology”

Neeraj Kumar, Abhishek Meghwal Abhishek Meghwal, خيريه حسن
1 citations
International Journal of Pharmaceutical Research and Applications
Drug Solubulity and Delivery Systems
0.79
article

“A Comprehensive Review on Pilot Plant Scale up And Platform Technology”

Neeraj Kumar, Abhishek Meghwal Abhishek Meghwal, خيريه حسن
article en
1 citations

Abstract

The pharmaceutical business uses pilot plant scaleup strategies to create reliable manufacturing procedures and turn lab-scale formulas into commercial products. The place called Pilot is where the five elements Material, Man, Method, and Machine are combined to manufacture things. A tiny, basic lab scale formula will be tested on a replica of the intended plant in the pilot plant before spending a significant amount of money on a production unit. Scaling up a pilot plant provides information on formula examination, reviewing the range of pertinent processing equipment, understanding raw material specifications, production rate, and physical space requirements. It can hold accurate documentation and reports for analysis in support of the GMP procedure. This review research discusses the parameters such as granulation feed rate,compression parameters, temperature and rate of drying will have acritical role in development of any solid dosage form. The primary goal of a pilot plant is to identify errors on a small scale and generate revenue on a large scale.

International Journal of Pharmaceutical Research and ApplicationsVol. 10(3)
Industry, innovation and infrastructure
Openalex Percentile: Top 26%
Drug Solubulity and Delivery Systems
0.79
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