Evidence for a JAK2/STAT3 proinflammatory and vasculogenic mimicry interrelated molecular signature in adipocyte-derived mesenchymal stromal/stem cells
Overall, we provide novel evidence that inhibiting JAK2/STAT3-regulated VM can also alter the acquisition of a proinflammatory signature and prevent the contribution of ADMSCs to alternative tumor neovascularization processes.
Authors
- Alain Zgheib
- Borhane Annabi (ORCID: https://orcid.org/0000-0002-5082-7183)
- Marie-Ève Roy
- Michel Desjarlais (ORCID: https://orcid.org/0000-0002-5828-1760)
- Carolane Veilleux
Institutions
- Université du Québec à Montréal (CA)
- Hôpital Maisonneuve-Rosemont (CA)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1186/s12964-025-02298-6
- Citations
- 1
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- Université du Québec à Montréal
- Natural Sciences and Engineering Research Council of Canada
- Fonds de recherche du Québec – Nature et technologies