Sphingolipid metabolism-related genes for the diagnosis of metabolic syndrome by integrated bioinformatics analysis and Mendelian randomization identification

PTPN18 and TAX1BP3 were identified as sphingolipid metabolism-related biomarkers for MetS, offering potential promising targets for therapeutic intervention.

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Publication Details

Journal
Diabetology & Metabolic Syndrome
Published
2025-06-19
DOI
https://doi.org/10.1186/s13098-025-01803-8
Primary Topic
Sphingolipid Metabolism and Signaling
Type
article
Field-Weighted Citation Impact
0.00
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article

Sphingolipid metabolism-related genes for the diagnosis of metabolic syndrome by integrated bioinformatics analysis and Mendelian randomization identification

Weidong Li, Zhifen Guan, Xinhao Zhou, Lili Xiang et al.
1 links
Diabetology & Metabolic Syndrome
Sphingolipid Metabolism and Signaling
article

Sphingolipid metabolism-related genes for the diagnosis of metabolic syndrome by integrated bioinformatics analysis and Mendelian randomization identification

Weidong Li, Zhifen Guan, Xinhao Zhou, Lili Xiang, Haitao Wang, Yao Wang, Yueming Huang, Naisheng Deng, Jun Ouyang, Bohao Cheng, Qixing Zhong
article en

Abstract

PTPN18 and TAX1BP3 were identified as sphingolipid metabolism-related biomarkers for MetS, offering potential promising targets for therapeutic intervention.

Diabetology & Metabolic SyndromeVol. 17(1)
Guangdong Medical College (CN), Zhongshan People's Hospital (CN)
Zero hunger
Openalex Percentile: Top 87%
Sphingolipid Metabolism and Signaling
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Sphingolipid metabolism-related genes for the diagnosis of metabolic syndrome by integrated bioinformatics analysis and Mendelian randomization identification — Weidong Li, Zhifen Guan, et al. · Diabetology & Metabolic Syndrome (2025) | TGRS Research Map | TGRS