Dual-functional injectable adhesive hydrogel delivering ginger-derived doxorubicin vesicles for osteosarcoma recurrence suppression and post-resection wound healing
This study presents a multifunctional hydrogel that combines hemostasis, antioxidation, tissue repair, and recurrence prevention. The findings suggest that this integrated therapeutic approach holds substantial potential for clinical application in elderly osteosarcoma treatment, addressing critical postoperative challenges and improving patient outcomes.
Authors
- Zhenfa Zhang (ORCID: https://orcid.org/0000-0002-9627-2590)
- Hui Chen (ORCID: https://orcid.org/0000-0003-2866-7811)
- Dongsheng Yue
- Qiang Zhang (ORCID: https://orcid.org/0000-0002-8862-3098)
- Bin Zhang (ORCID: https://orcid.org/0000-0002-6286-6227)
- Changli Wang (ORCID: https://orcid.org/0000-0003-3508-2918)
- Yu Zhang (ORCID: https://orcid.org/0000-0002-5592-111X)
- Leina Sun
Institutions
- Tianjin Medical University Cancer Institute and Hospital (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-06-19
- DOI
- https://doi.org/10.3389/fbioe.2025.1609673
- Citations
- 2
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 1.35