[BMIM][Cl]-Mediated Eco-Friendly One-Pot Synthesis of Benzimidazole Derivatives Under Microwave and Ultrasound Irradiation

We present an eco-friendly and straightforward method for synthesizing benzimidazole derivatives through the multicomponent condensation of In the present work various substitute aromatic aldehydes were condensed with benzene-1,2-diamine to give 2-phenyl-1H-benzo[d]imidazole derivatives in the presence of 1-Butyl-3-Methylimidazolium Chloride as a catalyst in ethanol under conventional reflux condition, ultrasound irradiation in ethanol and microwave irradiation under solvent free condition for appropriate time.The one-pot synthesis, excellent isolated yield, underscores the efficiency of this environmentally conscious approach. Structural characterization was conducted using analytical techniques, including Fourier Transform Infrared Spectroscopy (FT-IR) and 1H and 13C Nuclear Magnetic Resonance (NMR) Spectroscopy. The electronic synthesis of benzimidazole derivatives, facilitated by the catalytic action of 1-Butyl-3-Methylimidazolium Chloride, has proven highly effective in achieving maximum yields.