Functional connectivity alterations of the pregenual anterior cingulate cortex by ketamine and the modulation by lamotrigine

The findings support the hypothesis that ketamine's favourable effects, reflected by enhanced FC within key neural networks, may be attributable to glutamate release.

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Publication Details

Journal
Journal of Psychopharmacology
Published
2025-06-19
DOI
https://doi.org/10.1177/02698811251346705
Primary Topic
Treatment of Major Depression
Type
article
Field-Weighted Citation Impact
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article

Functional connectivity alterations of the pregenual anterior cingulate cortex by ketamine and the modulation by lamotrigine

David Weigner, Anne Weigand, Christian Keicher, Luisa Carstens et al.
Journal of Psychopharmacology
Treatment of Major Depression
article

Functional connectivity alterations of the pregenual anterior cingulate cortex by ketamine and the modulation by lamotrigine

David Weigner, Anne Weigand, Christian Keicher, Luisa Carstens, Christian F. Beckmann, Marvin Sören Meiering, Maarten Mennes, Rita Hertrampf, Simone Grimm, Andreas Wunder, Matti Gärtner
article en

Abstract

The findings support the hypothesis that ketamine's favourable effects, reflected by enhanced FC within key neural networks, may be attributable to glutamate release.

Journal of PsychopharmacologyVol. 39(10)
Boehringer Ingelheim (Germany) (DE), University of Zurich (CH), Humboldt-Universität zu Berlin (DE), MSB Medical School Berlin (DE), University Hospital of Zurich (CH), Freie Universität Berlin (DE), Charité - Universitätsmedizin Berlin (DE)
Openalex Percentile: Top 84%
Treatment of Major Depression
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