Enhancing mindfulness and compassion through an ayahuasca-inspired formulation containing N,N-DMT and harmine: A randomized controlled trial in healthy subjects
In line with previous studies on traditional botanical ayahuasca, our findings support the notion that the DMT/harmine formulation might have therapeutic potential through its ability to acutely enhance mindfulness and compassion. Continuing studies in therapeutic settings are needed to further elucidate the mechanisms of action of ayahuasca-inspired formulations.
Authors
- Daniel Meling (ORCID: https://orcid.org/0000-0001-9118-5431)
- Ilhui A Wicki (ORCID: https://orcid.org/0000-0002-5511-7981)
- Helena Aicher (ORCID: https://orcid.org/0000-0001-5915-7086)
- Milan Scheidegger (ORCID: https://orcid.org/0000-0003-1313-2208)
- Dario Dornbierer (ORCID: https://orcid.org/0000-0001-9946-2069)
- Michael J. Mueller (ORCID: https://orcid.org/0000-0001-9165-0903)
Institutions
- University of Freiburg (DE)
- University of Zurich (CH)
- University Medical Center Freiburg (DE)
- ETH Zurich (CH)
Publication Details
- Journal
- Journal of Psychopharmacology
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1177/02698811251344689
- Primary Topic
- Psychedelics and Drug Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Fundação Bial