Formulation and Evaluation of Topical Antifungal Gel Containing Itraconazole by Cold Mechanical Method

The present study involves the formulation and evaluation of a topical antifungal gel containing Itraconazole using the cold mechanical method. Itraconazole, a broad-spectrum antifungal agent, was incorporated into a gel base to enhance skin penetration and patient compliance. The gel was made with carbopol as a gelling agent and tested for pH, spreadability, drug content, and antifungal activity. The results indicated that the gel was stable, effective, and suitable for topical use against fungal infections