Pre-Clinical Evaluation of Therapeutic Potential of Prunetin as a Hepatoprotective Agent
The term “hepatoprotective” describes a substance’s capacity to shield the liver from harm. This may entail lowering inflammation, encouraging liver cell regeneration, or limiting damage from toxins. The current study's findings indicated that prunetin had phenolic content, proteins, amino acids, sterols, glycosides, saponins, flavonoids, alkaloids, and carbs. Of all the flavonoids, prunetin's hepatoprotective action is caused by glycosides and phenolic compounds. To determine the appropriate dosage of the non-toxic prunetin, additional acute toxicity research was conducted. According to an acute toxic research, the safe doses are 20 mg/kg and 40 mg/kg.
Authors
- Abdul Hameed (ORCID: https://orcid.org/0000-0001-8999-5662)
- Hina Afaq
- Yash Srivastav (ORCID: https://orcid.org/0009-0008-5017-6529)
- Divya Singh
Publication Details
- Journal
- International Journal of Pharmaceutical Research and Applications
- Published
- 2025-03-01
- DOI
- https://doi.org/10.35629/4494-100316171640
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 0.00