Establishment of a novel alloxan‐induced rabbit model exhibiting unique diabetic retinal neuropathy features assessed via <scp>ERG</scp> + <scp>VEP</scp>
A single intravenous injection of 80 mg/kg alloxan effectively and safely induced DRN in rabbits, resulting in neural retina damage, thereby establishing this model as an ideal model for DRN research.
Authors
- Bai Li (ORCID: https://orcid.org/0000-0002-5412-6106)
- Zhi‐Zhou Shi (ORCID: https://orcid.org/0000-0002-0967-375X)
- Xiaojing Dong (ORCID: https://orcid.org/0000-0003-3842-6958)
- Zhong‐Jian Liu (ORCID: https://orcid.org/0000-0003-4390-3878)
- Xinlu Li (ORCID: https://orcid.org/0000-0002-3806-3993)
- Hu Han (ORCID: https://orcid.org/0000-0001-6010-1792)
- Wei He (ORCID: https://orcid.org/0000-0003-2377-7456)
- Yan Mei (ORCID: https://orcid.org/0009-0002-2128-1967)
- Chenchen Huang (ORCID: https://orcid.org/0009-0006-9093-9995)
- Defei Feng
Institutions
- Kunming University of Science and Technology (CN)
- First People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- Animal Models and Experimental Medicine
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1002/ame2.70032
- Citations
- 2
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.41
Funders
- National Natural Science Foundation of China
- Kunming Medical University
- Kunming University of Science and Technology