Comprehensive Overview: The History, Structure, Composition, and Mechanism of Ibuprofen
One typical non-steroidal anti-inflammatory medicine (NSAID) in the home is ibuprofen and this paper will discuss the aforementioned organic compound. In this work, the history, structure and composition, mechanism, binding and metabolism of ibuprofen are covered. The two researchers will attempt to explain different stages of the development of the drug as well as research surrounding the drug. Afterwards, the paper will cover functional groups, bonds, enantiomers of the drug. Lastly, the paper will delve into the more intricate workings of ibuprofen including the process of different synthesis of prostaglandin, ranging from PGF2, PGE2, PGD2 to TXA2, distribution of different prostaglandins in different human issues and functions of prostaglandins, differences between COX-1 and COX-2, how COX is binded, and primary and secondary metabolism.
Authors
- Ziyan Liu (ORCID: https://orcid.org/0000-0002-7604-0047)
- Zirong Jiang
Institutions
- John L. Miller Great Neck North High School (US)
- Shanghai Jinyuan Senior High School (CN)
Publication Details
- Journal
- Theoretical and Natural Science
- Published
- 2025-06-19
- DOI
- https://doi.org/10.54254/2753-8818/2025.24230
- Primary Topic
- Inflammatory mediators and NSAID effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00