A Study of ABCG2 Versus SLC2A9 in the Treatment of Gout

Describe the symptoms of gout, the number of deaths caused by gout, and the impact of gout in various countries, and analyze its pathogenic mechanisms. Treatment with two uric acid transporters, ABCG2 and SLC2A9, is used as drugs, from tracing the origin of ABCG2 and SLC2A9 to understanding their nomenclature and studying their chemical properties and then to the relationship between ABCG2 and SLC2A9 and gout, as well as the comparison of the mechanism of action of ABCG2 and SLC2A9. As a common disease with unclear pathogenic mechanisms, gout has limited drugs for treatment and large side effects; ABCG2 and SLC2A9 have obvious effects on gout by controlling the uric acid content in the body with almost no side effects.

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Publication Details

Journal
Theoretical and Natural Science
Published
2025-06-19
DOI
https://doi.org/10.54254/2753-8818/2025.24209
Primary Topic
Gout, Hyperuricemia, Uric Acid
Type
article
Field-Weighted Citation Impact
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article

A Study of ABCG2 Versus SLC2A9 in the Treatment of Gout

Z. Rong
Theoretical and Natural Science
Gout, Hyperuricemia, Uric Acid
article

A Study of ABCG2 Versus SLC2A9 in the Treatment of Gout

Z. Rong
article en

Abstract

Describe the symptoms of gout, the number of deaths caused by gout, and the impact of gout in various countries, and analyze its pathogenic mechanisms. Treatment with two uric acid transporters, ABCG2 and SLC2A9, is used as drugs, from tracing the origin of ABCG2 and SLC2A9 to understanding their nomenclature and studying their chemical properties and then to the relationship between ABCG2 and SLC2A9 and gout, as well as the comparison of the mechanism of action of ABCG2 and SLC2A9. As a common disease with unclear pathogenic mechanisms, gout has limited drugs for treatment and large side effects; ABCG2 and SLC2A9 have obvious effects on gout by controlling the uric acid content in the body with almost no side effects.

Theoretical and Natural ScienceVol. 115(1)
Taiyuan Heavy Industry (China) (CN)
Good health and well-being
Openalex Percentile: Top 84%
Gout, Hyperuricemia, Uric Acid
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