Expression patterns of estrogen and androgen receptors in NSCLC patients according to the PD-L1 profile
The estrogen pathway, particularly via ERα, plays a key role in PD-L1 expression and may contribute to tumor immune evasion. Antiestrogen therapy could represent a promising strategy to enhance immunotherapy efficacy in patients expressing ERs.
Authors
- María Rosa Ávila-Costa (ORCID: https://orcid.org/0000-0002-3000-186X)
- José Luis Ordóñez-Librado
- Jerónimo Rafael Rodríguez‐Cid (ORCID: https://orcid.org/0000-0001-8518-9065)
- Vianey Rodríguez-Lara
- Marco A. Cerbón
- Gala Cortés-Ramírez
- Itzel Amayrani Angeles-Torres
- Sally María Luisa Pedraza-Reyes
Institutions
- Evolutionary Genomics (United States) (US)
- Instituto Nacional de Neurología y Neurocirugía (MX)
- Universidad Latina (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-19
- DOI
- https://doi.org/10.3389/fimmu.2025.1602579
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05