Intravascular ultrasound evaluation of pulmonary hypertension in high-altitude patients with ventricular septal defect: a case report

This case demonstrates the first reported use of intravascular ultrasound to assess pulmonary artery structure in a patient with patent ductus arteriosus-associated pulmonary hypertension at extreme altitude. Intravascular ultrasound provided unique real-time insight into vascular remodeling that critically influenced clinical decision-making. It may serve as a valuable adjunct to standard diagnostics in high-risk or borderline operability cases, particularly in settings where histological evaluation is unfeasible. Broader use of intravascular ultrasound in congenital heart disease with pulmonary hypertension may enhance individualized risk assessment and optimize therapeutic strategies.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2025-06-19
DOI
https://doi.org/10.1186/s13256-025-05346-4
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
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article

Intravascular ultrasound evaluation of pulmonary hypertension in high-altitude patients with ventricular septal defect: a case report

Yuanguo Chen, Qi Qiao, Jing Li, Haibo Zhang et al.
Journal of Medical Case Reports
Pulmonary Hypertension Research and Treatments
article

Intravascular ultrasound evaluation of pulmonary hypertension in high-altitude patients with ventricular septal defect: a case report

Yuanguo Chen, Qi Qiao, Jing Li, Haibo Zhang, Yan Zhou
article en

Abstract

This case demonstrates the first reported use of intravascular ultrasound to assess pulmonary artery structure in a patient with patent ductus arteriosus-associated pulmonary hypertension at extreme altitude. Intravascular ultrasound provided unique real-time insight into vascular remodeling that critically influenced clinical decision-making. It may serve as a valuable adjunct to standard diagnostics in high-risk or borderline operability cases, particularly in settings where histological evaluation is unfeasible. Broader use of intravascular ultrasound in congenital heart disease with pulmonary hypertension may enhance individualized risk assessment and optimize therapeutic strategies.

Journal of Medical Case ReportsVol. 19(1)
Ya'an Polytechnic College (CN), Yan'an University (CN)
Good health and well-being
Openalex Percentile: Top 76%
Pulmonary Hypertension Research and Treatments
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Intravascular ultrasound evaluation of pulmonary hypertension in high-altitude patients with ventricular septal defect: a case report — Yuanguo Chen, Qi Qiao, et al. · Journal of Medical Case Reports (2025) | TGRS Research Map | TGRS