New-onset drug-resistant epilepsy in type 1 diabetes mellitus patient following COVID-19 vaccination: suspicious for autoimmune pathogenesis

This case exemplifies the diagnostic challenges inherent in autoimmune-associated epilepsy and underscores the necessity for prompt intervention. Glutamic acid decarboxylase (GAD65) antibody-associated autoimmune epilepsy should be suspected in adult-onset temporal lobe epilepsy with co-morbid type 1 DM with early initiation of immune therapy for better clinical outcomes.

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Publication Details

Journal
BMC Neurology
Published
2025-06-19
DOI
https://doi.org/10.1186/s12883-025-04126-3
Citations
1
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
1.39
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New-onset drug-resistant epilepsy in type 1 diabetes mellitus patient following COVID-19 vaccination: suspicious for autoimmune pathogenesis

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article

New-onset drug-resistant epilepsy in type 1 diabetes mellitus patient following COVID-19 vaccination: suspicious for autoimmune pathogenesis

Michael Baghdadi, Nirmeen A. Kishk, Ibrahim Elmenshawi, Amani M. Nawito, Hadeer Elsaeed AboElfarh, Sally Shaaban, Ahmed Hamdy, Mohamed Eladrousi, Marwa El Sayed Elktob, Mohamed Elfieshy
article en
1 citations

Abstract

This case exemplifies the diagnostic challenges inherent in autoimmune-associated epilepsy and underscores the necessity for prompt intervention. Glutamic acid decarboxylase (GAD65) antibody-associated autoimmune epilepsy should be suspected in adult-onset temporal lobe epilepsy with co-morbid type 1 DM with early initiation of immune therapy for better clinical outcomes.

BMC NeurologyVol. 25(1)
Cairo University (EG), Mansoura University (EG), Ministry of Communication and Information Technology (ET), Ministry Of Health (FJ), Ministry of Health and Population (EG)
Good health and well-being
Openalex Percentile: Top 19%
Autoimmune Neurological Disorders and Treatments
1.39
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