Clinical and Genetic Profile of 35 Patients with Glycogen Storage Disease Type 1b: A Comparative Analysis Before and During SGLT2 Inhibitor Therapy
Our findings suggest that empagliflozin therapy significantly improves neutropenia recovery by reducing the frequency of recurrent infections and inflammatory bowel disease (IBD)-like symptoms. This improvement was demonstrated by a marked reduction in skin and mucosal infections, particularly oral ulcers, as well as an increase in hemoglobin levels and overall stature.
Authors
- Sonja Pavlović (ORCID: https://orcid.org/0000-0002-2915-1641)
- Bozica Kecman
- Maja Stojiljković (ORCID: https://orcid.org/0000-0003-0625-2009)
- Maja Djordjevic Milosevic
- Ivona Kovačević
- Anita Skakić (ORCID: https://orcid.org/0000-0002-1213-4458)
- Sara Stankovic
Institutions
- University of Belgrade (RS)
Publication Details
- Journal
- Molecular Diagnosis & Therapy
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1007/s40291-025-00795-5
- Citations
- 2
- Primary Topic
- Glycogen Storage Diseases and Myoclonus
- Type
- article
- Field-Weighted Citation Impact
- 3.34
Funders
- Science Fund of the Republic of Serbia