Genomic evolution of <i><scp>EGF</scp>‐<scp>CFC</scp></i> genes in deuterostomes
We propose that subsequent to EGF-CFC family expansion in tetrapods, Tdgf1B (Xenopus Tdgf1.2) acquired specialization in the left-right patterning cascade, and then after its translocation in eutherians to a different chromosomal location, CFC1 has maintained that specialization.
Authors
- Paul A. Trainor (ORCID: https://orcid.org/0000-0003-2774-3624)
- Natalia A. Shylo (ORCID: https://orcid.org/0000-0002-0466-896X)
Institutions
- Stowers Institute for Medical Research (US)
- University of Kansas Medical Center (US)
Publication Details
- Journal
- Developmental Dynamics
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1002/dvdy.70051
- Citations
- 1
- Primary Topic
- Developmental Biology and Gene Regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Stowers Institute for Medical Research
- Eunice Kennedy Shriver National Institute of Child Health and Human Development