Relationship between anthropometric parameters and serum monocyte chemoattractant protein-1 levels in adult subjects

Anthropometry is a method used to assess the human body's size, proportion, and composition. Anthropometric values can be used as diagnostic criteria for obesity. Obesity contributes to low-grade systemic inflammation; when macrophages invade adipose tissue, they produce pro-inflammatory cytokines, which are the source of inflammation in these tissues. Monocyte Chemoattractant Protein-1 is among the essential chemokines that govern monocyte migration and invasion. The principal fibroblasts, astrocytes, monocytes/macrophages, smooth muscle cells, endothelial cells, epithelial cells, and microglial cells are regulated by many cytokines and other factors. This study seeks to examine the connection between anthropometric factors (weight, height, body mass index, upper arm circumference, waist, and hip circumference) with blood MCP-1 levels in adult individuals. Eighty subjects, including twenty obese women, twenty non-obese women, twenty obese men, and twenty non-obese men, participated in the cross-sectional study design using an observational analytical approach. Serum MCP-1 levels, height (r = -0.162 p = 0.150), and weight (r = 0.172 p = 0.128) did not correlate, according to the data. Serum MCP-1 levels, waist circumference (r = 0.265 p = 0.017), and BMI (r = 0.275 p = 0.014) are all correlated. Hip circumference and serum MCP-1 levels did not correlate (r = 0.185 p = 0.100). Serum MCP-1 levels and mid-upper arm circumference (MUAC) did not correlate in either obese or non-obese adult individuals (r = 0.150 p = 0.183). According to the study's findings, serum MCP-1 levels in adult subjects who are obese and those who are not increase with waist circumference and body mass index (BMI).