Longitudinal Overlap and Metabolite Analysis in Spectroscopic MRI-Guided Proton Beam Therapy in Pediatric High-Grade Glioma
Longitudinal sMRI enhanced metabolic tracking in pHGG, detects early tumor changes, and refines RT targeting beyond structural imaging. This first in-kind study highlights the potential of sMRI biomarkers in tracking treatment effects and emphasizes the complementary roles of metabolic and radiographic metrics in evaluating therapy response in pHGG.
Authors
- Kartik Reddy (ORCID: https://orcid.org/0000-0001-7435-1864)
- Eduard Schreibmann
- Abinand C. Rejimon (ORCID: https://orcid.org/0000-0001-9273-0024)
- Vicki Huang (ORCID: https://orcid.org/0000-0003-3029-4700)
- Natia Esiashvilli
- Bree R. Eaton (ORCID: https://orcid.org/0000-0003-2431-2933)
- Anuradha G. Trivedi (ORCID: https://orcid.org/0000-0002-3348-4529)
- Karthik K. Ramesh
- Hyunsuk Shim
Institutions
- Georgia Institute of Technology (US)
- Emory University (US)
- Children's Healthcare of Atlanta (US)
Publication Details
- Journal
- Tomography
- Published
- 2025-06-19
- DOI
- https://doi.org/10.3390/tomography11060071
- Citations
- 1
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 1.52