Elevated factor VIIa—antithrombin complexes are associated with stroke or cardiovascular death in patients with atrial fibrillation
This study is the first to show that high plasma FVIIa-AT complexes are independently associated with thromboembolic events or CV death in AF, suggesting the need for more potent anticoagulation to suppress the residual TF-mediated coagulation.
Authors
- Elżbieta Paszek (ORCID: https://orcid.org/0000-0002-8389-9407)
- Elżbieta Szczygieł‐Pilut (ORCID: https://orcid.org/0000-0002-9290-9312)
- Michał Błaż (ORCID: https://orcid.org/0000-0002-5811-6773)
- Elżbieta Pociask (ORCID: https://orcid.org/0000-0001-8938-1089)
- Anetta Undas (ORCID: https://orcid.org/0000-0003-3716-1724)
Institutions
- Jagiellonian University (PL)
- John Paul II Hospital (PL)
- Institute of Cardiology (PL)
- AGH University of Krakow (PL)
Publication Details
- Journal
- European Journal of Clinical Investigation
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1111/eci.70091
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Uniwersytet Jagielloński Collegium Medicum