Predictors of diabetic ketoacidosis in patients with insulin‐deficient diabetes phenotype initiating <scp>SGLT2</scp> inhibitors
SGLT2i use in patients with an insulin-deficient phenotype is associated with increased DKA risk, particularly in those with HbA1c >9% and BMI ≤25 kg/m<sup>2</sup>. Clinicians should exercise caution in these patients, carefully assessing risks and implementing mitigation strategies to ensure safe use.
Authors
- Matan Joel Cohen (ORCID: https://orcid.org/0000-0002-0091-2216)
- Rena Pollack (ORCID: https://orcid.org/0000-0001-6771-337X)
- Gil Leibowitz (ORCID: https://orcid.org/0000-0002-6915-4361)
- Anat Tsur (ORCID: https://orcid.org/0000-0001-8573-4705)
- Avivit Cahn (ORCID: https://orcid.org/0000-0002-7830-9994)
Institutions
- Hebrew University of Jerusalem (IL)
- Hadassah Medical Center (IL)
- Clalit Health Services (IL)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1111/dom.16545
- Citations
- 6
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 7.77