Gray matter microstructure alterations with excess extra-cellular free water contribute to cognitive dysfunction in bipolar disorder: A comparative analysis with white matter pathology
In BD, cognitive function was correlated with gray matter microstructure alterations, reflected by increased extracellular FW in relevant brain areas, more strongly than with white matter impairment according to decreased FA.
Authors
- Yasuhito Nagai (ORCID: https://orcid.org/0000-0002-9254-5547)
- Wataru Uchida
- Toshimasa Fujimura
- Koji Kamagata (ORCID: https://orcid.org/0000-0001-5028-218X)
- Tadafumi Kato (ORCID: https://orcid.org/0000-0001-7856-3952)
- Shigeki Aoki (ORCID: https://orcid.org/0000-0003-2821-0651)
- Rinako Iseki
Institutions
- Juntendo University (JP)
- Juntendo University Urayasu Hospital (JP)
- Juntendo University Hospital (JP)
Publication Details
- Journal
- NeuroImage
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1016/j.neuroimage.2025.121342
- Citations
- 2
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- Japan Agency for Medical Research and Development
- Juntendo Institute of Mental Health