Differential impact of hepatitis delta virus replication and expression of viral antigens on the cellular kinome profile
A detailed analysis of the impact of HDV on the cellular kinome was established. Based on this, host-factors, single hits and even entire signalling cascades were identified. These advance understanding of HDV life cycle, and support development of novel therapeutics, yet also help to assess pathogenic processes.
Authors
- Kai‐Henrik Peiffer (ORCID: https://orcid.org/0000-0002-3757-4476)
- Mirco Glitscher (ORCID: https://orcid.org/0000-0002-8799-7565)
- Keerthihan Thiyagarajah (ORCID: https://orcid.org/0000-0002-1381-8093)
- Eberhard Hildt (ORCID: https://orcid.org/0000-0002-3020-9564)
Institutions
- Goethe University Frankfurt (DE)
- University Hospital Münster (DE)
- University Hospital Frankfurt (DE)
- Paul Ehrlich Institut (DE)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1186/s12964-025-02290-0
- Citations
- 1
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 1.32