Protein-Bound Uremic Toxins Removal with Medium Cut-Off Membranes: A Pilot Study Showing No Superiority over High-Flux Dialysis

MCO membranes did not demonstrate superior removal of protein-bound toxins compared to HF membranes in this pilot study. These findings highlight the need for alternative strategies, such as adsorption, and larger studies to define the clinical utility of MCO technology.

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Publication Details

Journal
Blood Purification
Published
2025-06-18
DOI
https://doi.org/10.1159/000546721
Citations
1
Primary Topic
Dialysis and Renal Disease Management
Type
article
Field-Weighted Citation Impact
1.43
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article

Protein-Bound Uremic Toxins Removal with Medium Cut-Off Membranes: A Pilot Study Showing No Superiority over High-Flux Dialysis

Armando Rojas, Francisco J. Aranda, Gonzalo Ramírez‐Guerrero, Cristian Pedreros‐Rosales et al.
1 citations
Blood Purification
Dialysis and Renal Disease Management
1.43
article

Protein-Bound Uremic Toxins Removal with Medium Cut-Off Membranes: A Pilot Study Showing No Superiority over High-Flux Dialysis

Armando Rojas, Francisco J. Aranda, Gonzalo Ramírez‐Guerrero, Cristian Pedreros‐Rosales, Constanza Verdugo, Barbara Segovia‐Hernández
article en
1 citations

Abstract

MCO membranes did not demonstrate superior removal of protein-bound toxins compared to HF membranes in this pilot study. These findings highlight the need for alternative strategies, such as adsorption, and larger studies to define the clinical utility of MCO technology.

Blood PurificationVol. 54(8)
University of Concepción (CL), Catholic University of the Maule (CL), Hospital Carlos Van Buren (CL), Hospital Las Higueras (CL)
Clean water and sanitation
Openalex Percentile: Top 19%
Dialysis and Renal Disease Management
1.43
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