Type 2 diabetes and depression via microvascular dysfunction, neurodegeneration, inflammation, advanced glycation end products ( <scp>AGEs</scp> ), and arterial stiffness
The association between type 2 diabetes and a higher risk of clinically relevant depressive symptoms is partly mediated by microvascular dysfunction, neurodegeneration, AGEs and arterial stiffness.
Authors
- Tos T. J. M. Berendschot (ORCID: https://orcid.org/0000-0002-8101-939X)
- Miranda T. Schram (ORCID: https://orcid.org/0000-0001-8113-7604)
- Hans Bosma (ORCID: https://orcid.org/0000-0003-4333-4564)
- Indra L. M. Steens (ORCID: https://orcid.org/0000-0002-9025-2011)
- Bastiaan E. de Galan (ORCID: https://orcid.org/0000-0002-1255-7741)
- Simone J. P. M. Eussen (ORCID: https://orcid.org/0000-0003-0559-6838)
- Thomas T. van Sloten (ORCID: https://orcid.org/0000-0003-2870-482X)
- Alfons J.H.M. Houben
Institutions
- Radboud University Nijmegen (NL)
- Utrecht University (NL)
- Maastricht University Medical Centre (NL)
- Erasmus MC (NL)
- Radboud University Medical Center (NL)
- University Medical Center Utrecht (NL)
- Maastricht University (NL)
- Department of Health (TW)
- Zorginstituut Nederland (NL)
- Eindhoven University of Technology (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1111/dom.16527
- Citations
- 8
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 4.62
Funders
- Sanofi
- Health Foundation Limburg
- Diabetes Fonds
- Novo Nordisk
- Stichting De Weijerhorst
- European Regional Development Fund
- CARIM School for Cardiovascular Diseases, Universiteit Maastricht
- Care and Public Health Research Institute, Universiteit Maastricht
- NUTRIM School of Nutrition and Translational Research in Metabolism
- Cilag