Neutrophil extracellular traps are increased in the airways of obese asthmatic patients
NETs are increased in obese individuals with asthma and are associated with body mass index. Sputum eDNA is associated with poorer lung function and is also associated with sputum NETs. Hence, NETs may be a potential therapeutic target for obese asthmatic patients.
Authors
- Katherine J. Baines (ORCID: https://orcid.org/0000-0002-4240-6581)
- Laura R C Dowling (ORCID: https://orcid.org/0000-0002-9747-2631)
- Lisa G. Wood (ORCID: https://orcid.org/0000-0002-0941-9225)
- Evan J. Williams (ORCID: https://orcid.org/0000-0003-0532-2060)
- Sarah C. E. Stanton (ORCID: https://orcid.org/0000-0002-3562-4644)
Institutions
- Hunter Medical Research Institute (AU)
- University of Newcastle Australia (AU)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1183/23120541.00025-2025
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Health and Medical Research Council