Ciliated epithelial cell differentiation at air–liquid interface and respiratory syncytial virus infection using animal-free media and substrates
Transitioning to include more animal-free medium and substrates for primary cell culture and viral propagation will help improve the ethical standing of research and offer more human-relevant models for studying viral diseases in the future.
Authors
- Paolo De Coppi (ORCID: https://orcid.org/0000-0002-1659-0207)
- Robert E. Hynds (ORCID: https://orcid.org/0000-0002-2170-8791)
- Christopher O’Callaghan (ORCID: https://orcid.org/0000-0002-8633-2473)
- Claire M. Smith (ORCID: https://orcid.org/0000-0002-8913-0009)
- Rosalind L. Smyth (ORCID: https://orcid.org/0000-0003-1406-6142)
- Jenny Herbert (ORCID: https://orcid.org/0000-0003-4179-775X)
- Machaela Palor (ORCID: https://orcid.org/0000-0003-4276-5346)
- Elizabeth Haughey (ORCID: https://orcid.org/0009-0001-9676-4763)
Institutions
- Manchester Academic Health Science Centre (GB)
- Great Ormond Street Hospital (GB)
- University of Manchester (GB)
- Institute of Infection and Immunity (CA)
- University College London (GB)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1183/23120541.00028-2025
- Citations
- 1
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Animal Free Research UK
- Biotechnology and Biological Sciences Research Council