Acute and Long-Term Immune-Treatment Strategies in Anti-LGI1 Antibody–Mediated Encephalitis
This study provides Class IV evidence that for patients with anti-LGI1 Ab-mediated encephalitis, rituximab prevents relapses and acute methylprednisolone is associated with favorable outcomes at 12 months.
Authors
- Catherine Meade
- Richard Macdonell (ORCID: https://orcid.org/0000-0001-6604-3968)
- Charles Benjamin Malpas (ORCID: https://orcid.org/0000-0003-0534-3718)
- James Broadley (ORCID: https://orcid.org/0000-0002-9988-3944)
- Andrew Duncan (ORCID: https://orcid.org/0000-0002-7817-7637)
- Terence John O'Brien (ORCID: https://orcid.org/0000-0002-7198-8621)
- Laurie McLaughlin
- Jayashri Kulkarni (ORCID: https://orcid.org/0000-0002-3875-5623)
- Udaya Seneviratne (ORCID: https://orcid.org/0000-0003-0182-9702)
- Robb Wesselingh (ORCID: https://orcid.org/0000-0002-5898-3287)
- James Beharry (ORCID: https://orcid.org/0000-0002-4932-954X)
- Tomáš Kalinčík (ORCID: https://orcid.org/0000-0003-3778-1376)
- Katherine Buzzard (ORCID: https://orcid.org/0000-0003-4039-9303)
- Helmut Butzkueven (ORCID: https://orcid.org/0000-0003-3940-8727)
- Ernest Butler (ORCID: https://orcid.org/0000-0003-0551-5671)
- Liora ter Horst
- Mastura Monif (ORCID: https://orcid.org/0000-0001-6404-9768)
- Amy G. Brodtmann (ORCID: https://orcid.org/0000-0001-9466-2862)
- Christina Kazzi (ORCID: https://orcid.org/0000-0001-6737-5489)
- David Gillis (ORCID: https://orcid.org/0000-0002-1659-5243)
- Fielding Joanne
- Anneke van der Walt (ORCID: https://orcid.org/0000-0002-4278-7003)
- Nabil Seery (ORCID: https://orcid.org/0000-0001-6446-868X)
- Genevieve Skinner
- Cassie Nesbitt (ORCID: https://orcid.org/0000-0002-5895-3459)
- Tracie Tan
- Stefan Blum (ORCID: https://orcid.org/0000-0002-2702-3742)
- Andrew Swayne (ORCID: https://orcid.org/0000-0002-8041-5593)
- Simon Broadley (ORCID: https://orcid.org/0000-0002-9429-4307)
- Sarah Griffith (ORCID: https://orcid.org/0000-0002-7087-8703)
- Meaghan Clough (ORCID: https://orcid.org/0000-0001-5962-3681)
- Joshua Yap (ORCID: https://orcid.org/0000-0002-3982-7836)
- Marie O’Shea
- Bruce Taylor (ORCID: https://orcid.org/0000-0003-2807-0070)
- Noushin Chini Foroush
- Todd A. Hardy (ORCID: https://orcid.org/0000-0003-4145-3172)
- Mirasol Forcadela (ORCID: https://orcid.org/0000-0002-3268-4457)
- Wendyl D’Souza (ORCID: https://orcid.org/0000-0002-1750-5131)
- Amy J. Halliday (ORCID: https://orcid.org/0000-0001-6032-4347)
- Hannah Ford
- David M. Tarlinton (ORCID: https://orcid.org/0000-0001-9928-686X)
- Paul G. Sanfilippo (ORCID: https://orcid.org/0000-0002-1778-9154)
- Sudarshini Ramanathan (ORCID: https://orcid.org/0000-0002-0294-9768)
- Stephen Reddel (ORCID: https://orcid.org/0000-0002-0169-3350)
- Rubina Alpitsis
- Paul Beech (ORCID: https://orcid.org/0000-0003-3871-3682)
- Nicola Warren (ORCID: https://orcid.org/0000-0002-0805-1182)
- Tiffany Rushen
- Yong Wang (ORCID: https://orcid.org/0000-0003-0989-9764)
- Meng Tan
- Brian Long (ORCID: https://orcid.org/0000-0003-4999-124X)
- Yang Tran
- Richard Wong
- J.Philip MacIntyre
- Alison Craig
- Wen Wen Zhang
- Fong Cheng Yi
- Kevin Ko
- Chris Kindt
- Miri Forcadel
Institutions
- The University of Sydney (AU)
- The University of Queensland (AU)
- The University of Melbourne (AU)
- Geelong Hospital (AU)
- Concord Repatriation General Hospital (AU)
- Princess Alexandra Hospital (AU)
- Royal Hobart Hospital (AU)
- St Vincent's Hospital Melbourne (AU)
- Eastern Health (AU)
- Peninsula Health (AU)
- Monash Health (AU)
- Melbourne Health (AU)
- Alfred Health (AU)
- Austin Health (AU)
- Monash University (AU)
Publication Details
- Journal
- Neurology Neuroimmunology & Neuroinflammation
- Published
- 2025-06-19
- DOI
- https://doi.org/10.1212/nxi.0000000000200412
- Citations
- 4
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.56