A Randomized Phase I Trial Evaluating Safety and Pharmacokinetics of Single and Multiple Ascending Doses of Eclitasertib, a RIPK1 Inhibitor, in Healthy Participants

Authors

Yong Lin (ORCID: https://orcid.org/0000-0002-5710-5036)
Annie J. Kruger (ORCID: https://orcid.org/0000-0001-8227-5996)
Robert J. Pomponio (ORCID: https://orcid.org/0009-0001-3069-6542)
Christine Farenc
Salvatore Badalamenti (ORCID: https://orcid.org/0000-0002-0394-0730)
P Clot
Heribert Staudinger (ORCID: https://orcid.org/0000-0001-5670-8591)
Tillmann Krahnke

Institutions

Morristown Medical Center (US)
Sanofi (France) (FR)
Sanofi (United States) (US)
C3I (United States) (US)
Sanofi (Germany) (DE)

Publication Details

Journal: Advances in Therapy
Published: 2025-06-19
DOI: https://doi.org/10.1007/s12325-025-03255-y
Citations: 1
Primary Topic: Cell death mechanisms and regulation
Type: article
Field-Weighted Citation Impact: 0.81

Funders

Sanofi
Denali Therapeutics

Controls

|||

ALL TIME

JAN

FEB

MAR

APR

MAY

JUN

JUL

AUG

SEP

OCT

article

A Randomized Phase I Trial Evaluating Safety and Pharmacokinetics of Single and Multiple Ascending Doses of Eclitasertib, a RIPK1 Inhibitor, in Healthy Participants

Yong Lin, Annie J. Kruger, Robert J. Pomponio, Christine Farenc et al.

Jun 19, 2025

1 citations

Advances in Therapy

Cell death mechanisms and regulation

0.81

article

A Randomized Phase I Trial Evaluating Safety and Pharmacokinetics of Single and Multiple Ascending Doses of Eclitasertib, a RIPK1 Inhibitor, in Healthy Participants

Yong Lin, Annie J. Kruger, Robert J. Pomponio, Christine Farenc, Salvatore Badalamenti, P Clot, Heribert Staudinger, Tillmann Krahnke

June 19, 2025article en

1 citations

Abstract

No abstract available for this paper.

Advances in TherapyVol. 42(8)

Morristown Medical Center (US), Sanofi (France) (FR), Sanofi (United States) (US), C3I (United States) (US), Sanofi (Germany) (DE)

Sanofi, Denali Therapeutics

Good health and well-being

Openalex Percentile: Top 27%

Cell death mechanisms and regulation

0.81

DOI Open Access PDF OpenAlex

AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.