Assessment of Burden of Partial Response to Standard Doses of Proton Pump Inhibitors in Patients with Clinically Diagnosed Gastroesophageal Reflux Disease: A Real-World Evidence Study in India

A significant proportion of patients with GERD were partial responders to PPIs. Pantoprazole and rabeprazole had high patient adherence across disciplines. Both pantoprazole DDR 80 mg once daily (OD) and 40 mg BD demonstrated significant symptom reduction in partial responders, supporting their use in optimizing GERD management in Indian clinical settings.

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Publication Details

Journal
Drugs - Real World Outcomes
Published
2025-06-19
DOI
https://doi.org/10.1007/s40801-025-00497-8
Primary Topic
Gastroesophageal reflux and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Assessment of Burden of Partial Response to Standard Doses of Proton Pump Inhibitors in Patients with Clinically Diagnosed Gastroesophageal Reflux Disease: A Real-World Evidence Study in India

Amey Mane, Sadhna Joglekar, Rajiv Saikia, Yogesh Garje et al.
Drugs - Real World Outcomes
Gastroesophageal reflux and treatments
article

Assessment of Burden of Partial Response to Standard Doses of Proton Pump Inhibitors in Patients with Clinically Diagnosed Gastroesophageal Reflux Disease: A Real-World Evidence Study in India

Amey Mane, Sadhna Joglekar, Rajiv Saikia, Yogesh Garje, Suyog Mehta, Neeraj Markandeywar, Sunil Gupta, Ashwini Satpathy, Chintan Khandhedia, Shruti Dharmadhikari, Praveen Sharma, S.I. Perí
article en

Abstract

A significant proportion of patients with GERD were partial responders to PPIs. Pantoprazole and rabeprazole had high patient adherence across disciplines. Both pantoprazole DDR 80 mg once daily (OD) and 40 mg BD demonstrated significant symptom reduction in partial responders, supporting their use in optimizing GERD management in Indian clinical settings.

Drugs - Real World OutcomesVol. 12(3)
St. Augustine College (US), National Institute of Pathology (IN), Cipla (India) (IN), Sun Pharma (India) (IN), Sun Pharma Advanced Research (India) (IN), Malaviya National Institute of Technology Jaipur (IN)
Openalex Percentile: Top 79%
Gastroesophageal reflux and treatments
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Assessment of Burden of Partial Response to Standard Doses of Proton Pump Inhibitors in Patients with Clinically Diagnosed Gastroesophageal Reflux Disease: A Real-World Evidence Study in India — Amey Mane, Sadhna Joglekar, et al. · Drugs - Real World Outcomes (2025) | TGRS Research Map | TGRS